Tiny, Menacing Microclots May Explain Long COVID’s Symptoms

SOURCES:

Hannah Davis, founding member and researcher, Patient-Led Research Collaborative.

Etheresia (Resia) Pretorius, PhD, head of department and distinguished research professor, Physiological Sciences Department, Faculty of Science, Stellenbosch University, South Africa.

Douglas Kell, PhD, research chair in systems biology, Department of Biochemistry, University of Liverpool, U.K.

Michael VanElzakker, PhD, neuroscientist, Massachusetts General Hospital and Harvard Medical School; co-founder, PolyBio Research Foundation.

Biochemical Journal: “A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications.”

Preprint, medRxiv: “Prevalence of amyloid blood clots in COVID-19 plasma.”

Cardiovascular Diabetology: Prevalence of symptoms, comorbidities, fibrin amyloid microclots and platelet pathology in individuals with Long COVID/Post-Acute Sequelae of COVID-19 (PASC).”

Bioanalytical Sciences Group: “Long COVID and the role of fibrin amyloid (fibrinaloid) microclots.”

U.S. Government Accountability Office: “Science and Tech Spotlight: Long Covid.”

The Guardian: “Could microclots help explain the mystery of long Covid?”

Frontiers in Microbiology: “Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms.”

Nature Microbiology: “Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome.”

Bioscience Reports: “SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microclot formation in COVID-19.”

Clinical Infectious Diseases: “Persistent Circulating Severe Acute Respiratory Syndrome Coronavirus 2 Spike Is Associated With Post-acute Coronavirus Disease 2019 Sequelae.”

YouTube: “The ‘Microclot’ Pathology of Long Covid With Dr Jaco Laubscher,” Gez Medinger:.

Preprint, Research Square: “Combined triple treatment of fibrin amyloid microclots and platelet pathology in individuals with Long COVID/ Post-Acute Sequelae of COVID-19 (PASC) can resolve their persistent symptoms”

The BMJ: “Long covid patients travel abroad for expensive and experimental ‘blood washing.’”

Studies, Surveys and Supplements: “Frequently Asked Questions: Nattokinase, Lumbrokinase & Serrapeptase.”