viral

Structural changes in HIV maturationNascent HIV particles assemble at the plasma membrane of an infected cell and bud into a membrane-enveloped, immature virion. Assembly and budding are driven by a polyprotein called Gag, which consists of…

Added value of PCR testing for COVID-19During the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, polymerase chain reaction (PCR) tests were generally reported only as binary positive or negative outcomes. However,…

Assays for detecting pathogens are used primarily to diagnose infections. Epidemiologists accumulate results from these tests in time series of case reports to conduct disease surveillance, a cornerstone of public health. During the…