vaccine

SummaryA powerful new weapon could one day join the global fight against malaria, especially to help people who need temporary protection from the deadly disease. Drugs and bed nets can to some extent already protect against the disease,…

PHOTO: CAMERON DAVIDSONFinally, in the United States, colleges and universities are ramping up for a relatively normal school year. Most pandemic restrictions have been lifted and—barring any unforeseen new coronavirus variants—parents and…

The highly contagious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects the respiratory tract and is transmitted, in part, by respiratory droplets and aerosols. Consequently, unvaccinated people are encouraged to wear…

AbstractOngoing SARS-CoV-2 vaccine development is focused on identifying stable, cost-effective, and accessible candidates for global use, specifically in low and middle-income countries. Here, we report the efficacy of a rapidly scalable,…

A boost from infectionDuring clinical trials of severe acute respiratory syndrome coronavirus 2 vaccines, no one who had survived infection with the virus was tested. A year after the pandemic was declared, vaccination of previously…

SummaryThe startlingly poor performance revealed last week for a COVID-19 vaccine made by the German company CureVac isn't just a disappointment, it's a scientific puzzle. The company blames the rapidly changing pandemic virus. But several…

AbstractThe side effects of SARS-CoV-2 vaccines are often troubling but may merely reflect transient production of type I interferons, a normal physiological response to contact with invading microorganisms.The development of multiple…

The cytokines interleukin-4 (IL-4) and IL-13 play important, nonredundant roles in the pathogenesis of asthma. Monoclonal antibodies against IL-4 receptor α (IL-4Rα), which inhibit both IL-4 and IL-13 signaling, can effectively ameliorate…

AbstractPatients with kidney failure are at increased risk for SARS-CoV-2 infection making effective vaccinations a critical need. It is not known how well mRNA vaccines induce B and plasma cell responses in dialysis patients (DP) or kidney…

Science's COVID-19 reporting is supported by the Heising-Simons FoundationA trial aims to test messenger RNA vaccines for COVID-19 in pregnant Africans, like this woman receiving a sonogram at an AIDS care center in South Africa.PHOTO: AP…