Structural

PHOTO: WENDIE BERGIn 1953, the proposed structure of DNA magnificently linked biological function and structure. By contrast, 4 years later, the first elucidation of the structure of a protein—myoglobin, by Kendrew and colleagues—revealed…

SummaryHigh-performance alloys play a critical role in demanding engineering applications in manufacturing, infrastructure, and transportation (1). In structural applications, they must be strong, ductile, durable, and damage tolerant.…

Target site selection in CAST systemsExciting genomic engineering possibilities exist for natural integration systems called transposons, which have coopted CRISPR/Cas systems. An unexplained feature of these systems involves how they…

Defenses against SARS-CoV-2 variantsOur key defense against the COVID-19 pandemic is neutralizing antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus elicited by natural infection or vaccination. Recent…

SARS-CoV-2 from alpha to epsilonAs battles to contain the COVID-19 pandemic continue, attention is focused on emerging variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that have been deemed variants of…

Shifting frames to make more proteinsSevere acute respiratory syndrome coronavirus 2 critically depends on the ribosomal frameshifting that occurs between two large open reading frames in its genomic RNA for expression of viral replicase.…