receptor

Blocking neuroinflammation at the blood-brain barrierDemyelinating chronic inflammatory conditions such as multiple sclerosis are associated with entry of leukocytes into the CNS vasculature through the blood-brain barrier. Calvier et al.…

Accessory proteins and nicotinic receptorsAcetylcholine was the first neurotransmitter identified, and nicotinic acetylcholine receptors (nAChRs) were the first neurotransmitter receptors isolated. Recent studies have identified a multitude…

INTRODUCTIONCentral to our understanding of immunity are the signaling pathways of the innate immune system. Prototypical examples include the pathways activated by the Toll-like receptors (TLRs) and the nucleotide-binding leucine-rich…

T cells are thought to integrate information from multiple encounters with antigen-presenting cells to become activated. To explore how the dynamics of T cell receptor signaling influence such a process, Harris et al. developed an optically…