Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years…
Circulating autoantibodies (auto-Abs) neutralizing high concentrations (10 ng/mL, in plasma diluted 1 to 10) of IFN-α and/or - are found in about 10% of patients with critical COVID-19 pneumonia, but not in subjects with asymptomatic…