Microbiota

SummaryAnimals have coevolved with complex communities of microorganisms living on barrier tissues, referred to as the microbiota or commensals. The microbiota controls immune function not only locally within barrier tissues but also…

Treatment with immune checkpoint blockade therapies that target the programmed death receptor 1 (PD-1) pathway has revolutionized care for patients with melanoma and numerous other cancers. In melanoma, median overall survival rates for…