immunotherapy

SummaryAnimals have coevolved with complex communities of microorganisms living on barrier tissues, referred to as the microbiota or commensals. The microbiota controls immune function not only locally within barrier tissues but also…

The antitumor efficacy of cancer immunotherapy can correlate with the presence of certain bacterial species within the gut microbiome. However, many of the molecular mechanisms that influence host response to immunotherapy remain elusive.…

AbstractType 1 diabetes (T1D) is an autoimmune disease in which T cells attack and destroy the insulin-producing β cells in the pancreatic islets. Genetic and environmental factors increase T1D risk by compromising immune homeostasis.…

Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy By Marie Siwicki, Nicolas A. Gort-Freitas, Marius Messemaker, Ruben Bill, Jeremy Gungabeesoon, Camilla Engblom, Rapolas Zilionis,…