immune

SummaryIncreasing evidence suggests that immune system development begins in utero and is heavily influenced by the maternal immune status during gestation (1). Pregnancy is associated with suppression of the maternal immune system to…

RESULTSBroad immune remodelling in COVID-19 patientsTo assess the dynamics of immune responses elicited by SARS-CoV-2 infection, we collected PBMCs from COVID-19 patients at the time of acute infection (hereafter indicated as “infection”),…

SARS-CoV-2 from alpha to epsilonAs battles to contain the COVID-19 pandemic continue, attention is focused on emerging variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that have been deemed variants of…

SARS-CoV-2 from alpha to epsilonAs battles to contain the COVID-19 pandemic continue, attention is focused on emerging variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that have been deemed variants of…

Calcium signaling for host cell deathIn response to microbial pathogens, some plants kill off their own cells to limit further spread of infection. The Toll/Interleukin-1 receptor/Resistance class of nucleotide-binding leucine-rich repeat…

SummaryOther than a placebo-controlled, clinical trial lasting many months and involving tens of thousands of people, is there any way to be sure a COVID-19 vaccine will work? Many researchers say the vaccines already in use offers a…

AbstractOrgan transplant patients have poor immune responses to COVID-19 vaccines; thus designing vaccine strategies to protect this vulnerable population from SARS-CoV-2 infection is crucial.Effective vaccines against viruses, including…

AbstractThe inclusion of infants in the SARS-CoV-2 vaccine roll-out is important to prevent severe complications of pediatric SARS-CoV-2 infections and to limit transmission and could possibly be implemented via the global pediatric vaccine…

Science's COVID-19 reporting is supported by the Heising-Simons FoundationFaced with short supplies of COVID-19 vaccines and unforeseen side effects, some countries have adopted an unproven strategy: switching shots midstream. Most…