functional

More species in warm watersPast patterns of diversity can be used as a baseline for understanding how current human-induced changes are affecting biodiversity. Womack et al. looked at mollusk fossils from 40 million years ago in New Zealand…

Defenses against SARS-CoV-2 variantsOur key defense against the COVID-19 pandemic is neutralizing antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus elicited by natural infection or vaccination. Recent…

SummaryOver the past several years, advances in RNA sequencing have led to an increased appreciation of the prevalence and function of noncoding RNAs, including long noncoding RNAs (lncRNAs). These are typically expressed in a…

Go big or you'll get lostRational mutagenesis is a common approach to investigating or engineering enzyme function in vitro, but the ease with which one can manipulate protein sequences belies many pitfalls in connecting sparse activity…