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Alzheimers

Phenotyping Alzheimer’s disease with blood tests

Alzheimer's disease (AD) is characterized by brain protein aggregates of amyloid-β (Aβ) and phosphorylated tau (pTau) that become plaques and tangles, and dystrophic neurites surrounding the plaques, which are accompanied by downstream…

Treatments for Alzheimer’s disease emerge

Few of life's experiences evoke greater apprehension than a diagnosis of Alzheimer's disease (AD). Virtually unknown to the public until the 1980s, it is alone among the 10 most common fatal diseases of developed nations in lacking a…

Alzheimer’s drug approval spotlights blood tests

SummaryIn the wake of the controversial U.S. regulatory approval of the Alzheimer's drug aducanumab, physicians expect many patients with memory problems will want to know whether they are eligible. But a definitive diagnosis is expensive…

Alzheimer’s drug approved despite murky results

SummaryThe antibody aducanumab this week became the first new Alzheimer's disease drug approved in the United States since 2003, and the first ever that aims to interfere with the underlying disease process. In a controversial decision, the…